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  • T.D.E. Wedding Expands as Leading Chinese Wedding Planner in San Francisco: Embracing Tradition with Personalized Touch

    T.D.E. Wedding Expands as Leading Chinese Wedding Planner in San Francisco: Embracing Tradition with Personalized Touch

    T.D.E. Wedding, well known for its event planning services, has announced an expansion aimed at meeting the needs of clients who want unique wedding experiences. With a focus on cultural inclusivity and personalized service, T.D.E. Wedding is reaching out to broader audiences. The company is particularly interested in helping couples blend traditional and contemporary styles into their ceremonies.

    A key focus for T.D.E. Wedding is the Chinese wedding market in San Francisco. As a top Chinese wedding planner in San Francisco, the company understands the complexity and richness of Chinese wedding traditions. They have made sure their planners are knowledgeable about these customs. From intricate tea ceremonies to lively receptions, T.D.E. Wedding provides expert advice in crafting meaningful and authentic ceremonies. Incorporating traditional Chinese elements adds depth to any wedding, and T.D.E. Wedding aims to make this process smooth for every couple.

    Potential clients can explore the comprehensive wedding planning services offered by T.D.E. Wedding on their official website, which provides detailed information about their all-inclusive packages and additional offerings like photography, makeup, and floral arrangements.

    Otis Fang of T.D.E. Wedding shared, “We aim to give all couples a wedding that mirrors their cultural background and personal style. Expanding to be the leading Chinese wedding planner in San Francisco is a major step towards this goal. We want every couple to receive personalized care and a celebration that respects their heritage.”

    Beyond Chinese weddings, T.D.E. Wedding offers services that honor a variety of cultural backgrounds. This effort is part of a larger goal to make weddings more inclusive and reflective of the couple’s traditions. Each service is customized to meet the specific needs of the client, highlighting a commitment to personalized attention.

    Otis Fang added, “Understanding our clients’ traditions is key to providing a memorable experience. We collaborate closely with each couple to ensure their wedding day aligns with their vision, integrating traditional and modern elements. Our team is passionate about making each wedding truly reflect the couple’s journey.”

    By offering these tailored services, T.D.E. Wedding not only meets the growing demand for culturally-rich ceremonies but also sets a high standard in the wedding planning industry. Their professionals are trained to appreciate various cultural practices to ensure every event is as genuine as possible. This dedication defines the company’s mission.

    For those interested in unique offerings like their photo-booth services or to learn more about their event lighting options, visiting their website will provide detailed insights into how T.D.E. Wedding can enhance the atmosphere of any wedding.

    The expansion also leads to T.D.E. Wedding investing in resources and tools that support culturally specific ceremonies. This includes working with vendors who specialize in traditional elements, ensuring each detail of the wedding day is attended to with care. With this approach, couples can relax knowing their special day is in the hands of experts who respect their cultural needs.

    Couples who choose T.D.E. Wedding can look forward to a stress-free experience from beginning to end. The process is built on strong communication, ensuring that each wedding unfolds flawlessly, allowing clients to enjoy their day without worries.

    Through this expansion, T.D.E. Wedding stands out as a leader in culturally-inclusive wedding planning. Whether it’s a traditional Chinese wedding or any cultural celebration in San Francisco, T.D.E. Wedding is dedicated to crafting a ceremony that is both unique and personal. By committing to authenticity and personal service, T.D.E. Wedding continues to create weddings that are both memorable and meaningful.

    As the company moves forward, T.D.E. Wedding is committed to serving the diverse needs of couples who want to merge tradition with their own personal touches. As a notable Chinese wedding planner San Francisco, their mission aligns with a wider trend in the wedding industry toward inclusivity and cultural respect, emphasizing the significance of personalized service in creating truly unforgettable celebrations.

    The post T.D.E. Wedding Expands as Leading Chinese Wedding Planner in San Francisco: Embracing Tradition with Personalized Touch appeared first on Local News Hub.

  • Gladstone Commercial Corporation Earnings Call and Webcast Information

    Gladstone Commercial Corporation Earnings Call and Webcast Information

    MCLEAN, VA / ACCESS Newswire / October 30, 2025 / Gladstone Commercial Corporation (Nasdaq:GOOD) announces the following event:

    What:

    Gladstone Commercial Corporation’s Third Quarter Ended September 30, 2025 Earnings Call & Webcast

    When:

    Tuesday, November 4, 2025 @ 8:30 a.m. ET

    Website:

    https://event.choruscall.com/mediaframe/webcast.html?webcastid=vtJIsPxo

    How:

    By webcast — Log on to the web at the address above

    By phone — Please call (877) 407-9045

    Contact:

    Gladstone Commercial Corporation, (703) 287-5893

    A conference call replay will be available after the call and will be accessible through November 11, 2025. To hear the replay, please dial (877) 660-6853 and use playback conference number 13755539.

    If you are unable to participate during the live webcast, the call will also be archived on our website (www.gladstonecommercial.com).

    Gladstone Commercial Corporation is a real estate investment trust (“REIT”) focused on acquiring, owning and operating net leased industrial and office properties across the United States. Additional information can be found at www.gladstonecommercial.com.

    For further information: Gladstone Commercial Corporation, (703) 287-5893

    SOURCE: Gladstone Commercial Corporation

    View the original press release on ACCESS Newswire

  • Inspire Veterinary Partners Announces up to $10M in Financing at $1.00 per Share Through Cash and Transferred Securities

    Inspire Veterinary Partners Announces up to $10M in Financing at $1.00 per Share Through Cash and Transferred Securities

    VIRGINIA BEACH, VA / ACCESS Newswire / August 4, 2025 / Inspire Veterinary Partners, Inc. (NASDAQ:IVP) (“Inspire” or the “Company”), an owner and provider of pet health care services throughout the U.S., today announced that it has entered into a securities purchase agreement for the issuance and sale of securities under a new convertible preferred stock transaction. The consideration, consisting of a combination of cash and transferred securities, was valued at $1.00 per share.

    The gross proceeds to the Company from the offering are expected to be up to $10 million, including $6 million expected to be received through the investment of cash and securities at the first closing, and up to $4 million of cash that may be funded at one or more additional closings, at the election of the investors. The Company intends to use the net proceeds from the offering for general working capital and acquisitions of additional veterinary practices. The proceeds will also help to address current Nasdaq deficiencies around Shareholders Equity and extend cash on hand to maintain operations and extend runway.

    “As communicated earlier in 2025, the team at IVP is executing on our growth strategy and this offering helps to facilitate our objectives,” said President, Chairman and CEO, Kimball Carr, “With new acquisitions onboarded and record clinical hiring this year, I could not be prouder of our team for the continued progress being made across all departments within IVP.”

    This press release shall not constitute an offer to sell or the solicitation of an offer to buy these securities, nor shall there be any sale of these securities in any state or other jurisdiction in which such offer, solicitation or sale would be unlawful prior to the registration or qualification under the securities laws of any such state or jurisdiction.

    About Inspire Veterinary Partners, Inc.

    Inspire Veterinary Partners is an owner and provider of pet health care services throughout the US. As the Company expands, it expects to acquire additional veterinary hospitals, including general practice, mixed animal facilities, and critical and emergency care. For more information, please visit: www.inspirevet.com.

    Facebook | LinkedIn | X

    Forward-Looking Statements

    This press release contains forward-looking statements regarding the Company’s current expectations. These statements are not guarantees of future performance and are subject to certain risks, uncertainties and assumptions that are difficult to predict. Factors that could cause actual results to differ include, but are not limited to, statements by the Company relating to the completion of the offering, the satisfaction of customary closing conditions related to the offering, the intended use of proceeds from the offering, receipt of Stockholder Approval as well as risks and uncertainties related to the satisfaction of customary closing conditions related to anticipated acquisitions, or factors that result in changes to the Company’s anticipated results of operations related to acquisitions. These and other risks and uncertainties are described more fully in the section captioned “Risk Factors” in the Company’s public filings made with the Securities and Exchange Commission, including its Annual Report on Form 10-K and Quarterly Reports on Form 10-Q. Forward-looking statements contained in this announcement are made as of this date, and the Company undertakes no duty to update such information except as required under applicable law.

    Investor Contact

    CoreIR
    Matt Blazei
    516-386-0430
    mattb@coreir.com

    Press Contact

    CORE IR
    Matthew Cossel
    pr@coreir.com

    General Inquires

    Morgan Wood
    Mwood@inspirevet.com

    SOURCE: INSPIRE VETERINARY PARTNERS, INC.

    View the original press release on ACCESS Newswire

    The post Inspire Veterinary Partners Announces up to $10M in Financing at $1.00 per Share Through Cash and Transferred Securities appeared first on Local News Hub.

  • Phase 1 Clinical Ttrial of HIV Vaccine Starts in Africa to Evaluate Immune Responses to Highly Networked HIV T-Cell Epitopes

    Phase 1 Clinical Ttrial of HIV Vaccine Starts in Africa to Evaluate Immune Responses to Highly Networked HIV T-Cell Epitopes

    Led by a team of African researchers, first doses of the novel T cell-inducing GRAdHIVNE1 vaccine candidate have been given.

    HARARE, ZIMBABWE, ROME, ITALY, NEW YORK, NY, AND CAMBRIDGE, MA / ACCESS Newswire / August 4, 2025 / The Mutala Trust, ReiThera Srl (ReiThera), the Ragon Institute of Mass General Brigham, MIT, and Harvard (the Ragon Institute), and IAVI are pleased to announce that the first doses of an investigational HIV vaccine candidate have been administered. The vaccine candidate, Gorilla Adenovirus Vectored HIV Networked Epitopes Vaccine (GRAdHIVNE1), was first administered on July 28, 2025, at the Mutala Trust clinical trial site in Harare, Zimbabwe. This effort is made possible by a global collaboration and a team of African principal investigators who will lead the clinical research in South Africa and Zimbabwe (listed below). Vaccine immunogenicity will also be assessed locally by a network of state-of-the-art African research institutes: Cape Town HVTN Immunology Laboratory in Cape Town, African Health Research Institute in Durban, and the National Institute for Communicable Diseases in Johannesburg, South Africa.

    This Phase 1, first-in-human clinical trial will enroll approximately 120 healthy adults aged 18-50 years, including 48 people living with HIV who are virally suppressed on antiretroviral therapy (ART). The trial is designed to assess the safety and immunogenicity of the vaccine candidate in people living with and without HIV. Participants will receive either one or two doses of the investigational vaccine or a placebo and will be monitored over a period of 19 months for safety and immune responses.

    This clinical trial, IAVI C114, is sponsored by IAVI. GRAdHIVNE1 has been made possible by a collaborative effort. ReiThera developed the GRAd viral vector platform and manufactured the vaccine candidate, while the Ragon Institute designed the immunogen using novel strategies to identify protective HIV epitopes and facilitate their targeting by T cells. This clinical program is funded by the Gates Foundation.

    The IAVI C114 clinical trial is taking place at three clinical trial sites: the Mutala Trust Clinical Trial Site, in Harare, Zimbabwe; the Desmond Tutu Health Foundation (DTHF), in Cape Town, South Africa; and the Africa Health Research Institute (AHRI), in Durban, South Africa. To determine the vaccine candidate’s potential for relevance in sub-Saharan Africa, where disease burden is greatest, it is essential that the candidate be tested within communities affected by the epidemic.

    “This is a landmark moment for South Africa, Zimbabwe, and the continent. It shows the power of true partnership: IAVI’s sponsorship, ReiThera’s GRAd technology, the Ragon Institute’s innovative immunogen built on decades of science, and African investigators co-leading every phase of the trial. We are edging closer to an HIV vaccine, made possible by global collaboration, with clinical trials conducted in Africa, for Africa, and for the world.” said Dr. Tariro Makadzange, Clinical Trial Lead, Mutala Trust.

    “This trial represents the future of vaccine development, rooted in Africa, built through global partnerships, and designed for the communities most affected by HIV,” said Dr. Vincent Muturi-Kioi, HIV Vaccines Product Development Team Lead at IAVI.

    The vaccine candidate is designed to engage the immune system to recognize and target critical structural regions of HIV using a clinically validated, potent, T cell-inducing GRAd vector. This approach will be evaluated to assess the ability of the vaccine candidate to direct strong CD8+ T cell immune responses towards these vulnerable viral regions.

    “We are thrilled to be moving insights from our long-term studies of spontaneous elite controllers of HIV toward the development of GRAdHIVNE1 and its testing in Africa. We are truly grateful to the network of global and African partners that have come together to make the IAVI C114 trial a reality,” said Dr. Gaurav Gaiha, Associate Professor of Medicine at Harvard Medical School and Principal Investigator at the Ragon Institute of Mass General Brigham, MIT, and Harvard.

    Because CD8+ T cells induced by this vaccine hold promise for targeting HIV-infected cells, this clinical trial will also assess the safety and immune response in people living with HIV. These data will be used to assess the suitability of the vaccine candidate for the development of investigational HIV therapeutic and curative interventions.

    “We are enormously pleased with the launch of this Phase 1 trial representing the result of a successful global partnership,” said Stefano Colloca, CEO and co-Founder of ReiThera. “This candidate HIV vaccine, built on our GRAd platform, holds great promise to trigger a strong CD8 response targeting vulnerable viral regions.”

    Principal Investigators Leading Clinical Trial Sites:

    • Tariro Makadzange, Mutala Trust

    • Theodorah Rirhandzu Ndzhukule, DTHF

    • Limakatso Lebina, AHRI

    About IAVI

    IAVI is a global nonprofit scientific organization that works to develop vaccines and antibodies to prevent HIV and other infectious diseases, with a focus on innovation and equitable access. IAVI is the sponsor of this trial. Read more at www.iavi.org.

    IAVI media contact

    Heather Teixeira
    hteixeira@iavi.org

    About Mutala Trust

    Mutala Trust is founding member of Africa Clinical Research Network (ACRN) and is a site based in Harare, Zimbabwe. It is known for conducting high-quality, ethically sound clinical trials addressing diseases that affect African communities. Mutala is the clinical lead site for the study.

    Mutala Trustmedia contact

    coms@acrnhealth.com

    About ReiThera Srl.

    ReiThera Srl, an Italian CDMO specializing in technology and process development as well as GMP manufacturing of viral vectors for genetic vaccines and advanced therapies, is the developer and owner of the GRAd platform used for this HIV vaccine.

    ReiThera media contact

    communication@reithera.com

    About the Ragon Institute of Mass General Brigham, MIT, and Harvard

    The Ragon Institute of Mass General Brigham, MIT, and Harvard was established with a collaborative scientific mission among these institutions that brings scientists, clinicians and engineers together to harness the immune system to combat and cure human disease. They contributed to vaccine design. For more information, visit www.ragoninstitute.org

    Ragon Institutemedia contact

    ragoncommunications@mgh.harvard.edu

    SOURCE: IAVI

    View the original press release on ACCESS Newswire

    The post Phase 1 Clinical Ttrial of HIV Vaccine Starts in Africa to Evaluate Immune Responses to Highly Networked HIV T-Cell Epitopes appeared first on Local News Hub.

  • IRS Begins Scrutinizing “Cash-Only” Businesses in 2025 – Clear Start Tax Shares What to Expect

    IRS Begins Scrutinizing “Cash-Only” Businesses in 2025 – Clear Start Tax Shares What to Expect

    New IRS enforcement initiative targets restaurants, salons, and other cash-heavy operations as audit risk rises in 2025

    IRVINE, CA / ACCESS Newswire / August 4, 2025 / The IRS is ramping up its scrutiny of “cash-only” businesses in 2025, renewing enforcement efforts aimed at industries known for limited electronic records and underreported income. Restaurants, barbershops, nail salons, convenience stores, and similar businesses could face increased audit activity, according to tax professionals closely following the agency’s shift.

    Clear Start Tax, a national tax resolution firm, is advising small business owners who rely on cash transactions to take proactive steps to ensure their books are in order and avoid unnecessary penalties.

    “The IRS is targeting businesses with high cash volume because they often lack digital documentation, which makes them easier to flag for underreporting,” said a spokesperson for Clear Start Tax. “This year, the agency has new tools and data analytics that make it much easier to spot discrepancies in cash-heavy operations.”

    The enforcement push comes as part of a broader IRS strategy to close the “tax gap” – the difference between taxes owed and taxes actually collected – with the help of increased funding and advanced AI audit filters. Officials have stated they will focus on industries with historical patterns of noncompliance, particularly where income may be hidden or underreported.

    “We’re seeing a clear pattern: if your business isn’t using point-of-sale systems or bank deposits to track revenue, you’re at greater risk,” the Clear Start Tax spokesperson added. “Even businesses that aren’t intentionally evading taxes could get caught up in this if their recordkeeping is sloppy or inconsistent.”

    Clear Start Tax recommends that cash-based businesses conduct internal reviews, reconcile deposits with reported income, and consider working with professionals to prepare for potential audits. The firm has already seen a rise in inquiries from business owners seeking advice on how to respond to IRS notices or suspected underreporting claims.

    “Our message is simple – don’t wait for a letter from the IRS. Get ahead of it,” said the spokesperson. “A few small adjustments in how you document income today could save you thousands down the line.”

    By answering a few simple questions, taxpayers can find out if they’re eligible for the IRS Fresh Start Program and take the first step toward resolving their tax debt.

    The IRS has not announced specific audit targets, but experts say businesses operating with limited digital financial trails are already on the radar.

    About Clear Start Tax

    Clear Start Tax is a trusted tax resolution firm helping individuals and businesses nationwide resolve IRS debt, navigate audits, and find relief through established IRS programs. With a focus on transparency, compliance, and results, the firm has assisted thousands of taxpayers in regaining control of their financial futures.

    Need Help With Back Taxes?

    Click the link below:
    https://clearstarttax.com/qualifytoday/
    (888) 710-3533

    Contact Information

    Clear Start Tax
    Corporate Communications Department
    tech@clearstarttax.com
    (949) 800-4011

    SOURCE: Clear Start Tax

    View the original press release on ACCESS Newswire

    The post IRS Begins Scrutinizing “Cash-Only” Businesses in 2025 – Clear Start Tax Shares What to Expect appeared first on Local News Hub.

  • Tharimmune Issues Comprehensive Corporate Update including Lead TH104 as Critical National Security Solution Against Weaponized Fentanyl and TH023 Poised to Revolutionize Oral Antibody Delivery

    Tharimmune Issues Comprehensive Corporate Update including Lead TH104 as Critical National Security Solution Against Weaponized Fentanyl and TH023 Poised to Revolutionize Oral Antibody Delivery

    -Company closes approximately $5.47 million in equity financing in 2Q/3Q25
    -TH104 potentially fills a critical National Security Need against Weaponized Fentanyl
    TH023 may fulfill the promise of delivering a safe and effective oral antibody medication against inflammation
    -Company Strengthens Operational Leadership, Corporate Governance and Accounting

    RED BANK, NJ / ACCESS Newswire / August 4, 2025 / Tharimmune, Inc. (Nasdaq:THAR) (“Tharimmune” or the “Company”), a clinical-stage biotechnology company dedicated to developing innovative therapeutic candidates for inflammation, immunology, and critical unmet medical needs, today issued a comprehensive corporate update highlighting significant advancements across its pipeline. The update underscores the rapid progression of TH104 as a lead asset addressing critical national security risks posed by weaponized fentanyl, and the transformative potential of TH023 in pioneering oral antibody delivery for widespread inflammatory conditions.

    The Company has strengthened its financial position by successfully completing several equity financings and securing approximately $5.47 million in gross proceeds before deducting placement and legal fees, during the latter part of the second quarter and continuing into the third quarter of this year. The capital infusion underscores the strong confidence from existing investors, whose continued commitment reflects a clear recognition of the Company’s strategic vision and pipeline potential. We believe these proceeds will strategically accelerate the advancement of TH104, recognizing its paramount importance as a swiftly progressing national security asset, in addition to supporting general corporate purposes vital for the Company’s continued growth and operational efficiency.

    “Over the past year, Tharimmune has achieved considerable milestones, particularly in advancing our lead candidate TH104 to a potential NDA with clear direction from FDA on a pathway while demonstrating preclinical success with our oral antibody program, TH023,” stated Sireesh Appajosyula, Chief Executive Officer of Tharimmune. “Our strategic focus on high-impact solutions, from protecting military and first responders to redefining treatment paradigms for chronic inflammatory diseases, reflects our unwavering commitment to patient well-being and shareholder value.”

    TH104: A National Security Solution Against Weaponized Fentanyl and High-Potency Opioids

    Tharimmune’s lead asset, TH104, a buccal film formulation of nalmefene, has rapidly advanced with a regulatory pathway to address the escalating national security threat posed by weaponized fentanyl and other high-potency opioids like fentanyl.

    Addressing an Important National Security Threat: The U.S. government has increasingly recognized fentanyl and its related compounds as significant national security threats due to their extreme potency and potential for mass casualty incidents if weaponized. Incidents such as the 2002 Moscow theater hostage crisis, where aerosolized synthetic opioids were reportedly used, tragically demonstrated the devastating potential of such agents. In this critical context, Tharimmune explicitly positions TH104 as a direct response to this growing threat, aligning with the urgent need for specialized prophylactic medical countermeasures highlighted in recent U.S. Strategic National Stockpile (SNS) market assessments.

    Superiority and Convenience over Current Solutions: While existing solutions like naloxone auto-injectors are vital for emergency reversal, they often have a relatively short half-life (e.g., naloxone has a half-life of approximately 60-90 minutes to 2 hours). This can necessitate repeated dosing, particularly with longer-acting or highly potent synthetic opioids like fentanyl, which can have a significantly longer half-life (around 8 hours). TH104, which utilizes nalmefene, offers a crucial advantage with a significantly longer plasma half-life of approximately 8 to 11 hours. This extended duration of action means TH104 provides sustained protection, potentially reducing the need for continuous monitoring and potential multiple redosing in a high-risk environment. Furthermore, TH104’s buccal film formulation allows for rapid and convenient administration, a critical benefit for military personnel and chemical incident responders who may be wearing full protective gear, where intramuscular injections can be impractical or delayed.

    Positive FDA Feedback and Expedited Pathway: In a pivotal development, Tharimmune previously announced positive feedback from the FDA regarding the New Drug Application (NDA) path for TH104. Crucially, the FDA confirmed that no additional clinical trials appear to be necessary prior to a 505(b)(2) NDA submission for TH104’s proposed indication: “Temporary Prophylaxis of Respiratory and/or Nervous System Depression in Military Personnel and Chemical Incident Responders Entering an Area Contaminated with High-Potency Opioids.” This expedited pathway allows Tharimmune to leverage existing extensive safety and efficacy data for nalmefene, combined with the Company’s human pharmacokinetic data, enabling an “in silico” (computer simulation) submission model, significantly accelerating its potential availability.

    Robust Clinical Data and Metabolic Profile: Positive Phase 1 clinical data for TH104, presented at prominent conferences including Digestive Disease Week (DDW) and the European Association for the Study of the Liver (EASL) International Liver Congress in May 2025, highlights its distinct pharmacokinetic and metabolic profile. The data demonstrated that buccal administration achieves systemic exposure to nalmefene with reliable and predictable absorption and delayed phase 1 metabolism, potentially offering advantages for individuals with impaired liver function as potential added benefit. This scientific validation underpins TH104’s suitability as a critical medical countermeasure.

    Strengthened Expertise in National Security: Tharimmune has strategically fortified its leadership to advance TH104’s national security mission. James Gordon Liddy (CDR US Navy SEAL (Ret)), a renowned counter-terrorism and critical infrastructure expert, has been appointed to the Board of Directors and serves as a Key Strategic Advisor. His unparalleled expertise in national security and preparedness, including his role in designing and coordinating policy for the Global War on Terrorism and architecting the Navy’s Anti-Terrorism Force Protection Plan, provides invaluable guidance for the development and potential deployment of TH104 within national security frameworks.

    The Promise of Oral Antibody Delivery

    The administration of monoclonal antibodies (mAb), while highly effective for a range of chronic diseases, has historically been limited to intravenous (IV) infusions or subcutaneous injections. These parenteral routes often necessitate frequent clinic visits, specialized medical personnel for administration, and can be painful or inconvenient for patients, impacting adherence to long-term therapy. The development of an effective oral delivery method for antibodies would truly be a “game-changer,” revolutionizing patient access, convenience, and quality of life by transforming a complex, clinic-bound procedure into a simple, at-home pill. Overcoming the formidable physiological barriers of the gastrointestinal tract – including harsh pH environments, enzymatic degradation, and limited permeability for large molecules – has been a persistent challenge in biopharmaceutical development. We believe Tharimmune’s TH023 program is at the forefront of addressing this critical unmet need.

    TH023: Pioneering Oral Antibody Delivery for Inflammatory Conditions

    Tharimmune is developing TH023, a novel oral monoclonal antibody targeting Tumor Necrosis Factor-alpha (TNF-alpha), licensed through Intract Pharma (UK), which could potentially revolutionize the delivery of biologic therapies for a wide array of inflammatory conditions.

    Preclinical Validation: In an advancement for oral antibody delivery, Tharimmune in the past year announced positive preclinical results for TH023. Leveraging a proprietary protease enzyme stabilized platform (Soteria®), preclinical studies in a murine model successfully demonstrated oral delivery of infliximab, achieving serum concentrations significantly higher than standard therapeutic levels. The studies confirmed enzymatic protection and successful in vivo delivery to both local colonic tissue and systemic circulation, highlighting its potential for treating both local gastrointestinal diseases (like Inflammatory Bowel Disease) and systemic inflammatory conditions. This proprietary formulation showed superior tissue penetration compared to traditional permeation enhancers, underscoring the innovative nature of TH023.

    Revolutionizing Patient Care and Market Potential: This program originated from a strategic global licensing agreement with Intract Pharma for INT-023 (now TH023) in September 2024. Traditionally, TNF-alpha inhibitors like infliximab (Remicade®) are administered via intravenous infusions or subcutaneous injections, which may be burdensome for patients. TH023 aims to overcome these challenges, offering a convenient oral pill form that could dramatically improve patient compliance, quality of life, and reduce healthcare system burdens. With the global infliximab market in the multibillions, an oral formulation represents a substantial commercial opportunity by providing a differentiated, patient-preferred option that broadens access and potentially lowers overall treatment costs.

    Future Development: Building on these promising preclinical results, Tharimmune plans to optimize TH023’s formulation and dosing regimen and prepare for a first-in-human clinical trial within the next 12 months, marking a significant step towards bringing this transformative therapy to patients.

    Strengthening Corporate Governance and Leadership for Accelerated Growth

    Tharimmune has strategically enhanced its leadership and governance structure to support its ambitious pipeline advancements and future growth.

    Key Executive and Board Appointments: In addition to the strategic advisory role and Board appointment of James Gordon Liddy, Tharimmune has appointed Sireesh Appajosyula as Chief Executive Officer, leveraging his extensive experience in corporate development and operations. Vincent LoPriore, with decades of financial and investment banking experience, has been appointed Executive Chairman of the Board, further solidifying strategic oversight. The Board has also been strengthened by the appointments of Clay Kahler, bringing entrepreneurial leadership and expertise in life sciences manufacturing and clinical innovation, and Gary Stetz, a seasoned financial executive with extensive experience in accounting, finance, and corporate governance. These appointments collectively enhance the company’s operational, financial, and strategic capabilities as it advances its critical programs.

    Tharimmune remains dedicated to leveraging its innovative platforms to address high unmet medical needs and drive significant value for patients and shareholders alike.

    About Tharimmune, Inc.

    Tharimmune is a clinical-stage biotechnology company developing a diverse portfolio of therapeutic candidates in immunology, inflammation and oncology. Its lead clinical asset, TH104, is being developed for a specific indication via a 505(b)2 pathway for respiratory and/or nervous system depression in military personnel and chemical incident responders who may encounter environments contaminated with high-potency opioids. The expanded pipeline includes other indications for TH104, such as chronic pruritus in primary biliary cholangitis and TH023, a new approach to treating autoimmune diseases along with an early-stage multispecific biologic platform targeting unique epitopes against multiple solid tumors through its proprietary EpiClick Technology. The Company has a license agreement with OmniAb, Inc. to access their antibody discovery technology for targeting specified disease markers. Tharimmune continues to position itself as a leader in patient-centered innovation while working to deliver long-term value for shareholders. For more information, visit: www.tharimmune.com.

    Forward Looking Statements

    Certain statements in this press release are forward-looking within the meaning of the Private Securities Litigation Reform Act of 1995. All statements, other than statements of historical facts, contained in this press release, including statements regarding the timing and design of Tharimmune’s future Phase 2 trial, Tharimmune’s strategy, future operations, future financial position, projected costs, prospects, plans and objectives of management, are forward-looking statements. The words “anticipate,” “believe,” “continue,” “could,” “depends,” “estimate,” “expect,” “intend,” “may,” “ongoing,” “plan,” “potential,” “predict,” “project,” “target,” “should,” “will,” “would,” and similar expressions are intended to identify forward-looking statements, although not all forward-looking statements contain these identifying words. The Company may not actually achieve the plans, intentions, or expectations disclosed in these forward-looking statements, and you should not place undue reliance on these forward-looking statements. Actual results or events could differ materially from the plans, intentions and expectations disclosed in these forward-looking statements. Factors that may cause such differences, include, but are not limited to, those discussed under Risk Factors set forth in our Annual Report on Form 10-K for the year ended December 31, 2024 and other periodic reports filed by the Company from time to time with the Securities and Exchange Commission. In addition, the forward-looking statements included in this press release represent the Company’s views as of the date of this release. Subsequent events and developments may cause the Company’s views to change; however, the Company does not undertake and specifically disclaims any obligation to update or revise any forward-looking statements to reflect new information, future events or circumstances or to reflect the occurrences of unanticipated events, except as may be required by applicable law. These forward-looking statements should not be relied upon as representing the Company’s views as of any date subsequent to the date of this release.

    Contacts:

    Tharimmune, Inc.
    ir@tharimmune.com

    SOURCE: Tharimmune Inc.

    View the original press release on ACCESS Newswire

    The post Tharimmune Issues Comprehensive Corporate Update including Lead TH104 as Critical National Security Solution Against Weaponized Fentanyl and TH023 Poised to Revolutionize Oral Antibody Delivery appeared first on Local News Hub.

  • Pantomath Raises $30 Million in Series B Led by General Catalyst to Automate Data Operations with AI DRE Agent

    Pantomath Raises $30 Million in Series B Led by General Catalyst to Automate Data Operations with AI DRE Agent

    The funding accelerates the company’s mission to eliminate manual data operations by combining real-time monitoring, traceability and agentic AI to boost enterprise data reliability at scale.

    CINCINNATI, OH / ACCESS Newswire / August 4, 2025 / Pantomath, an AI-powered automated data operations platform, today announced it has secured $30 million in Series B funding to expand beyond traditional data observability to become the Operating System for Data Operations. The round was led by General Catalyst, a global investment and transformation company. Existing investors Sierra Ventures, Bowery Capital and Epic Ventures also participated in the round along with Hitachi Ventures, Cintrifuse Capital and Foster Ventures. This new round follows Pantomath’s $14 million Series A in late 2023 led by Sierra Ventures and will accelerate product innovation, go-to-market expansion, and strategic hiring to meet surging enterprise demand to automate manual tasks with AI DRE (Data Reliability Engineer) agents.

    “Enterprises today grapple with highly manual and reactive data operations to support their data pipelines and analytics products. 74% of organizations rely on downstream end-users to discover data reliability problems, leading to isolated manual troubleshooting and incident management that according to a CDO survey takes 90% of organizations hours to weeks to resolve. Data downtime, unreliable data, and failure to meet SLAs are common occurrences in large enterprises,” said Somesh Saxena, co-founder and President of Pantomath who lived through these challenges as a data leader at General Electric prior to co-founding Pantomath in 2022.

    “Our current foundation of auto-discovered data health graphs that automates cross-platform data monitoring positions us well to expand beyond real-time detection of data issues into full self-resolution of incidents with autonomous AI DRE agents,” said Shashank Saxena, co-founder and CEO of Pantomath.

    Since its initial product launch in 2023, Pantomath has experienced rapid growth across industries and now supports mission-critical analytics pipelines at leading Fortune 500 companies. “Pantomath slashed the time our teams spent tracking down broken pipelines. With their automated root-cause analysis, we resolve issues in minutes (not hours, days or weeks) so our business partners always have trusted data. Our data operations teams start and end their day with Pantomath,” said Andrew Connolly, Director of Site Reliability Engineering, WEX.

    The company also announced that Quentin Clark, a Managing Director at General Catalyst, is joining its board of directors. At General Catalyst, Clark has helped scale companies such as Glean, Windsurf (acquired by Cognition), and Neon (acquired by Databricks). “Enterprise data operations have remained stubbornly complex despite years of tooling. Pantomath is changing that with AI-native enterprise software that doesn’t just surface problems, it solves them. This is a shift from software as a passive tool to software that enacts work across the enterprise,” said Clark. “It’s the systems-of-record to systems-of-work transformation we’ve long envisioned.”

    About Pantomath

    Pantomath delivers automated data operations for modern enterprises, unifying real-time monitoring, cross-platform lineage, AI-driven root-cause and impact analysis into a single platform. By eliminating manual troubleshooting and reducing data downtime, Pantomath restores trust in data and unlocks productivity across analytics teams. The company is headquartered in Cincinnati, Ohio. Learn more at pantomath.com.

    About General Catalyst

    General Catalyst is a global investment and transformation company that partners with the world’s most ambitious entrepreneurs to drive resilience and applied AI.

    We support founders with a long-term view who challenge the status quo, partnering with them from seed to growth stage and beyond.

    With offices in San Francisco, New York City, Boston, Berlin, Bangalore, and London, we have supported the growth of 800+ businesses, including Airbnb, Anduril, Applied Intuition, Commure, Glean, Guild, Gusto, Helsing, Hubspot, Kayak, Livongo, Mistral, Ramp, Samsara, Snap, Stripe, Sword, and Zepto.

    For more: www.generalcatalyst.com, @generalcatalyst

    Media Contact:

    Nina Pfister
    MAG PR on behalf of Pantomath
    E: nina@mooringadvisorygroup.com

    SOURCE: Pantomath

    View the original press release on ACCESS Newswire

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  • EON Resources Inc. Announces Funding Design for the Settlement of the Seller Agreement and Debt Payoff and the Grayburg-Jackson Field Development

    EON Resources Inc. Announces Funding Design for the Settlement of the Seller Agreement and Debt Payoff and the Grayburg-Jackson Field Development

    HOUSTON, TX / ACCESS Newswire / August 4, 2025 / EON Resources Inc. (NYSE American:EONR) (“EON” or the “Company”) is an independent upstream energy company with 20,000 leasehold acres comprising two fields in the Permian Basin in southeast New Mexico. Today, the Company announces it has: (i) received multiple non-binding offers to fund the $41 to $53 million needed for the previously announced Purchase, Sale, Termination and Exchange Agreement with the Seller (“Seller Agreement”) that will result in (a) the restructure of the Company’s balance sheet by eliminating all current and future obligations to the Seller in a discounted manner, and (b) re-purchase of an overriding royalty interest (“ORRI”) equal to ten percent (10%) in the Grayburg-Jackson Field (Press Release on Seller Agreement as amended); and (ii) a farmout to an industry leader with a proven team for the previously announced San Andres horizontal drilling program (Press Release on horizontal drilling program) in the Grayburg-Jackson Field.

    Funding offers: Subject to execution of definitive documents, we expect to fund the $41 to $53 million using volumetric funding (“VMA”) via the sale of one or more ORRI packages. The schedule is to close and fund in approximately four weeks. The funding is to discharge our $20.5 million settlement with Seller and to retire the Company’s senior debt for $18.5 million. As disclosed in previous press releases, we expect the benefits to include:

    • Completion of our $20.5 million cash settlement with Seller that returns to EON the 10% ORRI; retirement of the $22 million Seller note ($15 million principal plus accrued interest); and return to treasury of the Seller preferred shares with redemption value of $24 million. This would create over $40 million in net value to the Company and its shareholders.

    • Retirement of its senior debt eliminating a $700,000 per month note payment with a payment substitution of an estimated incremental ORRI payment of $100,000 to $300,000 per month. A positive cash flow impact of $400,000 to $600,000 per month is expected.

    • Funds raised by the VMA and farm-in proceeds in excess of $41 million would be used to develop 45 in field waterflood patterns out of a remaining 150 waterflood patterns in our Seven Rivers formation.

    Farmout with Horizontal Drilling Program: In a separate farmout and drilling commitment transaction, EON has reached an agreement in principle with a private company with a proven team to develop reserves estimated to be up to 40 million barrels in the San Andres formation using a horizontal drilling program. We are targeting commencement of the initial San Andres horizontal drilling in the first quarter of 2026. EON expects that this will add over $100 million in PV-10 value to the Company. Details of this transaction are being withheld until the private company completes due diligence and closing occurs.

    “We could not be more pleased with the outcome of this raise that has resulted in connecting us with a world class Permian driller, and energy investors who are focused on Permian development opportunities,” said Dante Caravaggio, President and CEO of the Company. “To ensure we close in on schedule, we will proceed with one preferred and one backup funding source. Both sources look to the value of overriding royalties the Company could deliver in consideration of funding, with both sources in an advanced stage of due diligence. Simultaneously with the close, EON significantly improves cash flow reducing the need to use our ELOC facility.”

    More information will be released if we are successful in negotiating definitive documents and funding occurs, of which we can make no assurances at this stage.

    About the Grayburg-Jackson Oil Field Property

    LH Operating, LLC (“LHO”), a wholly owned subsidiary of EON, operates its holdings in New Mexico of oil and gas waterflood production comprising 13,700 contiguous leasehold acres, 342 producing wells and 207 injection wells situated on 20 federal and 3 state leases in the Grayburg-Jackson Oil Field. The Grayburg-Jackson Oil Field is located on the Northwest Shelf of the prolific Permian Basin in Eddy County, New Mexico.

    Leasehold rights of LHO include the Seven Rivers, Queen, Grayburg and San Andres intervals that range from as shallow as 1,500 feet to 4,000 feet in depth. The December 2024 reserve report from our third-party engineer, Haas and Cobb Petroleum Consultants, LLC (“Haas & Cobb” or “Cobb”), reflects LHO to have proven reserves of approximately 14.0 million barrels of oil and 2.8 billion cubic feet of natural gas. The mapped original-oil-in-place (“OOIP”) in the LHO leasehold is approximately 876 million barrels of oil in the Grayburg and San Andres intervals and 80 million barrels in the Seven Rivers interval for a total OOIP of approximately 956 million barrels of oil.

    Our primary production is currently from the Seven Rivers zone. In addition to proven reserves, the Company believes it may access an additional 34 million barrels of oil by adding perforations in the Grayburg and San Andres formations, plus another 40 million barrels from the horizontal drilling program in the San Andres. With proven oil reserves of over 15 million barrels, combined with the potential 74 million additional barrels from the Grayburg and San Andres zones, LHO should produce oil and a revenue stream for more than two decades with a low decline rate.

    About the South Justis Field Property

    The South Justis Field (“SJF”) is a carbonate reservoir, similar to the rest of the Permian. The SJF was first developed in the 1960’s and had an initial production in the 6,000 BOPD range. The waterflood implemented at a cost of $40 million dollars in the 1990’s by a major oil company had mediocre performance due to poor connectivity between wells, which indicates an opportunity for horizontal infill well drilling. The subsequent owners of the SJF had higher priorities, which led to an increase in idle wells with downhole failures, thus allowing the production to drop dramatically. The Seller acquired the field and has reactivated several wells with good results increasing the production of oil. This indicates that there are a significant number of wells that can be reactivated to increase production on existing wells.

    The SJF comprises 5,360 contiguous acres with 208 combined producing and injection wells with well spacing of 50 acres. The field is located in the Central Basin of the prolific Permian Basin in Lea County, New Mexico located approximately 100 miles from EON’s Grayburg-Jackson Oil Field property. The producing formations include the Glorietta, Blinebry, Tubb, Drinkard and Fusselman intervals that range from 5,000 feet to 7,000 feet in depth. The original-oil-in-place (“OOIP”) is approximately 207 million barrels of oil.

    About EON Resources Inc.

    EON is an independent upstream energy company focused on maximizing total returns to its shareholders through the development of onshore oil and natural gas properties in the United States. EON’s long-term goal is to maximize total shareholder value from a diversified portfolio of long-life oil and natural gas properties built through acquisition and through selective development, production enhancement, and other exploitation efforts on its oil and natural gas properties.

    EON’s Class A Common Stock trades on the NYSE American Stock Exchange (NYSE American: EONR) and the Company’s public warrants trade on the NYSE American Stock Exchange (NYSE American: EONR WS). For more information on EON, please visit the Company’s website: https://eon-r.com/

    Forward-Looking Statements

    This press release includes “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995 that involve risks and uncertainties that could cause actual results to differ materially from what is expected. Words such as “expects,” “believes,” “anticipates,” “intends,” “estimates,” “seeks,” “may,” “might,” “plan,” “possible,” “should” and variations and similar words and expressions are intended to identify such forward-looking statements, but the absence of these words does not mean that a statement is not forward-looking. Such forward-looking statements relate to future events or future results, based on currently available information and reflect the Company’s management’s current beliefs. A number of factors could cause actual events or results to differ materially from the events and results discussed in the forward-looking statements. Important factors – including the availability of funds, the results of financing efforts and the risks relating to our business – that could cause actual results to differ materially from the Company’s expectations are disclosed in the Company’s documents filed from time to time on EDGAR (see www.edgar-online.com) and with the Securities and Exchange Commission (see www.sec.gov). Readers are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date of this press release. Except as expressly required by applicable securities law, the Company disclaims any intention or obligation to update or revise any forward-looking statements whether as a result of new information, future events or otherwise.

    Investor Relations

    Michael J. Porter, President
    PORTER, LEVAY & ROSE, INC.
    mike@plrinvest.com

    SOURCE: EON Resources Inc.

    View the original press release on ACCESS Newswire

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  • Traveler Care Launches Global Medical Dispatch Platform to Help Travel Insurance Companies Cut ER Claims by 80%

    Traveler Care Launches Global Medical Dispatch Platform to Help Travel Insurance Companies Cut ER Claims by 80%

    NEW YORK CITY, NY / ACCESS Newswire / August 4, 2025 / Traveler Care, a breakthrough medical dispatch platform that brings urgent care directly to travelers in hotels, Airbnbs, and vacation rentals, has officially launched worldwide – offering travel insurance companies a high-impact solution to reduce avoidable emergency room and hospital claims.

    A Concierge Alternative to the Emergency Room

    Traveler Care connects travel insurers and their policyholders to a network of licensed, on-call providers who visit travelers in their accommodations – typically within 60-90 minutes. Conditions such as flu, food poisoning, dehydration, allergic reactions, UTIs, sprains, and wound care are treated on-site, eliminating the need for an ER visit.

    “In most cases, travelers just need a doctor – not a hospital admission,” said Eli Ofel, founder of Traveler Care. “We’ve built a scalable, insurer-ready solution that saves money and delivers a far better traveler experience.”

    Reduce Claims by $10,000+ Per Visit

    On average, a non-emergency ER visit costs travel insurers $13,000 to $17,000. Traveler Care treats the same conditions in-room for $1,700 to $3,000 – including diagnostics like mobile X-ray, ultrasound, IV therapy, and wound treatment.

    Pilot results have shown:
    – 83% reduction in ER claim volume
    – $10,000+ savings per case avoided
    – Higher satisfaction scores among travelers

    Built for Travel Insurance Partners

    Traveler Care is fully designed for insurance integration – with white-label and API options available for TPAs, underwriters, and global assistance networks.

    Platform features:
    – Nationwide U.S. coverage (with international expansion underway)
    – A robust dispatch network, for example companies like Leaa Health, Sickday, Heal, DocGo and more, any location that the travel insurance is experiencing high volume travel care will create a solution for that particular location within 60 days.
    – HIPAA-compliant documentation + one-click claims integration
    – Supports care delivery to hotels, Airbnbs, resorts, and serviced apartments

    Now Onboarding Insurance Companies Worldwide

    “We believe travel insurance companies shouldn’t just pay for care – they should deliver it smarter,” said Ofel. “With Traveler Care, you lower claims without compromising care.”

    Insurance providers, TPAs, and global assistance companies are invited to partner and deploy in-room urgent care as part of their medical benefit stack.

    Contact

    To schedule a private demo or receive our ROI case study:
    Visit www.traveler.care
    Email: partners@traveler.care
    Phone: +1 (347) 733-0563

    About Eli Ofel

    Eli Ofel is a serial entrepreneur and visionary behind multiple AI- and tech-powered platforms in healthcare, finance, and transportation. He is the founder and CEO of Traveler Care, Run.Vet, Leaa Health, 02.Market, and Lender.Market. With over 20 years of experience in healthcare operations, insurance workflows, and mobile logistics, Ofel brings a proven ability to bridge patient needs with scalable platform solutions – saving time, money, and lives.

    Contact Information

    Eli Ofel
    CEO
    eli@traveler.care
    3477330563

    .

    SOURCE: Traveler care

    View the original press release on ACCESS Newswire

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  • Venture Medical Position on CMS and MAC Skin Substitute Proposals

    Venture Medical Position on CMS and MAC Skin Substitute Proposals

    Venture Medical, LCC is sharing our position on the CY2026 Medicare Physician Fee Schedule and our future recommendations.

    MISSOULA, MT / ACCESS Newswire / August 3, 2025 / The proposed changes to skin substitute reimbursement and coverage in the CY2026 Medicare Physician Fee Schedule (PFS) and Future Effective Local Coverage Determinations (LCDs) are unprecedented and have sparked alarm across the advanced wound care community-particularly among mobile and office-based providers. These proposals, while nominally aimed at consistency and cost control, are based on flawed assumptions and methodologies that will result in reduced access, disrupted clinical practice, and long-term harm to patients and innovation. At Venture Medical we have been working for many months to help chart a course from the current unsustainable system to one which is rational and workable for patients, providers, industry and CMS. As many of you are preparing your comments on these policies, we wanted to share a summary of the direction in which we think the wound care community should be pushing. If you would like to discuss further, please reach out to us.

    Rescind the Future Effective LCDs

    • Originally designed to control cost-now redundant after CMS pricing reform.

    • Restrictive product selection harms access, limits clinician choice, and stifles innovation.

    • Sole reliance on RCTs ignores the value of real-world evidence (RWE) and other valid evidence.

    • Especially harmful for wounds like VLUs, PUs and surgical wounds where RCTs are limited or impractical.

    • Proposed update cycles span years-unworkable for a dynamic clinical field.

    Recommendations for the Future:

    • Support Clinical Flexibility

      • Products billed “incident to” clinician services should be selected by the clinician like other incident-to items.

      • Clinicians are best positioned to select appropriate products based on evidence, experience, and patient need.

      • Blocking new products from the market discourages new product innovation and restricts access

      • Incentivize evidence development with enhanced payments instead.

      • Arbitrary 8-application cap is not evidence-based and should also be removed.

    • Call for a National, Uniform LCD Framework

      • Establish consistent rules and documentation standards across all wound types.

      • Avoid regional disparities and overly prescriptive policies-maximize clinical flexibility for providers.

    • Replace ASP Model with a Higher Fixed-Fee Rate

      • ASP-based pricing is highly variable ($7-$13,117/cm²), unpredictable, and misaligned with clinical value.

      • Tiered reimbursement creates artificial hierarchies not tied to comparative outcomes.

      • Preferred model for 2026: single flat fee (e.g., $600-$1000/cm²) based on economic modeling

    • Fix Reimbursement Rates

      • CMS used only HOPD data-other sites of care must be included in rate calculations.

      • Accurate modeling supports a base rate of $550-$711/cm².

      • Raise non-facility physician application fees to >$500 for equity across care settings

      • Moderate overzealous audit activity

    • Support Innovation with Evidence-Based Enhancements

      • Establish favorable payment enhancements for products which can demonstrate high comparative effectiveness via RCT or RWE – similar to pass-through concept

      • Push for birth tissue product legislation tied to 2025 Health Services Bill.

      • Reformed biologics pathway for future tissue products.

    Contact Information

    Carey Brandenburg
    Director of Marketing & Communications
    careyb@venturemedical1.com
    800-881-1809

    .

    SOURCE: Venture Medical LLC

    View the original press release on ACCESS Newswire

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